meson setup <builddir> -Dopt=valueIf the build directory already exists, options are updated with their new value given on the command line (-Dopt=value). Unless --reconfigure is also specified, this won't reconfigure immediately. This has the same behaviour as meson configure <builddir> -Dopt=value.
Previous Meson versions were simply a no-op.
meson setup --clearcacheJust like meson configure --clearcache, it is now possible to clear the cache and reconfigure in a single command with meson setup --clearcache --reconfigure <builddir>.